Ni som var uppmärksamma hörde Ralf Sundberg nämna det arbete han höll på med tillsammans med Uffe Ravnskov i intervjun i avsnitt 79. Nu har BMJ (Brittish Medical Journal) publicerat en metstudie där de båda forskarna och läkarna, tillsammans med 14 andra, har studerat studier gjorda på LDL, dvs “ont kolesterol”, och dess koppling till hjärtsjukdom och död.
Studiens rubrik lyder:
“Lack of an association or an inverse association between low-density-lipoprotein cholesterol and mortality in the elderly: a systematic review”
Dvs, de konstaterar i studien att äldre personer med högre LDL, dvs “ont kolesterol” lever längre än de med lägre LDL. I 92% av de totalt 68 000 deltagarna i studierna sågs ett motsatt förhållande, dvs lägre dödstal med högre LDL-kolesterol. I resterande studier/deltagare hittade man inte något samband alls.
De konkluderar alltså att: “High LDL-C is inversely associated with mortality in most people over 60 years. ” och “elderly people with high LDL-C live as long or longer than those with low LDL-C”
Detta är ytterligare ett tecken på att statiner, kolesterolsänkande medicin, gör betydligt mer skada än nytta. Och med mycket biverkningar på köpet. Läs tidigare inlägg på temat kolesterol och statiner.
Studiens sammanfattning lyder så här:
“Objective It is well known that total cholesterol becomes less of a risk factor or not at all for all-cause and cardiovascular (CV) mortality with increasing age, but as little is known as to whether low-density lipoprotein cholesterol (LDL-C), one component of total cholesterol, is associated with mortality in the elderly, we decided to investigate this issue.
Setting, participants and outcome measures We sought PubMed for cohort studies, where LDL-C had been investigated as a risk factor for all-cause and/or CV mortality in individuals ≥60 years from the general population.
Results We identified 19 cohort studies including 30 cohorts with a total of 68 094 elderly people, where all-cause mortality was recorded in 28 cohorts and CV mortality in 9 cohorts. Inverse association between all-cause mortality and LDL-C was seen in 16 cohorts (in 14 with statistical significance) representing 92% of the number of participants, where this association was recorded. In the rest, no association was found. In two cohorts, CV mortality was highest in the lowest LDL-C quartile and with statistical significance; in seven cohorts, no association was found.
Conclusions High LDL-C is inversely associated with mortality in most people over 60 years. This finding is inconsistent with the cholesterol hypothesis (ie, that cholesterol, particularly LDL-C, is inherently atherogenic). Since elderly people with high LDL-C live as long or longer than those with low LDL-C, our analysis provides reason to question the validity of the cholesterol hypothesis. Moreover, our study provides the rationale for a re-evaluation of guidelines recommending pharmacological reduction of LDL-C in the elderly as a component of cardiovascular disease prevention strategies.”
Jag älskar ralf och hans hörliga sött att föreläsa o ifrågasätta dogmer, men efter att ha lät denna artikeln:
https://diabetes.nu/aderforkalkning-ldl-hdl-kolesterol-statiner-studier/
Börjar jag fundera lite mer. Det känns ändå som att Ralf och Ulf har rätt. Jag har i a f slutat med statiner!